Endocrine Abstracts

Japan has been regarded as a nongoitorous country due to the regular intake of iodine-rich food. However, nationwide information on current status of iodine intake is not available because there is no survey system for iodine nutrition in Japan.Objective: The objectives of this study is to characterize current iodine status in Japan.Methods: Since 2002 we have conducted studies on iodine nutrition in the Metropolitan area including...

Aim: Vitamin D insufficiency is associated with an increase in PTH, which might be critical for an increase in bone fragility. However, the role of endogenous PTH in vitamin D insufficiency-induced increase in fracture risk still remains unclear. The present study was performed to examine the relationships among vitamin D insufficiency, bone fragility, PTH and sclerostin, which is produced by osteocytes and inhibits bone formation by inhibiting the Wnt pathway.<p class="ab...

We present a case of severe malignant pheochromocytoma complicated with intestinal pseudo-obstruction, which was refractory to conventional therapies but reacted to intravenous administration of an α-blocker, phentolamine.Malignant pheochromocytoma typically metastasizes to bones, liver, lungs, and lymph nodes, and average 5-year survival rate in the patient with metastases is approximately 50%. Treatment options for malignant pheochromocytoma inclu...